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These mimic the action of the natural GLP-1 hormone in such a way: G activates adenylyl cyclase (AC), increases cAMP, activates protein kinases (PKA), and results in more calcium (Ca) in the cytosol

& Eide, G

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Studies have documented high GST expression in various tumor cells, such as cancers of the gastrointestinal tract, 6 pancreas, 22 breast, 23 liver, 24 lymphoma, 25 as well as melanoma